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Enzymatic C‐to‐C Protein Ligation

Transpeptidase‐catalyzed protein and peptide modifications have been widely utilized for generating conjugates of interest for biological investigation or therapeutic applications. However, all known transpeptidases are constrained to ligating in the N‐to‐C orientation, limiting the scope of attaina...

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Detalles Bibliográficos
Autores principales:	Rehm, Fabian B. H., Tyler, Tristan J., de Veer, Simon J., Craik, David J., Durek, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303898/ https://www.ncbi.nlm.nih.gov/pubmed/35018698 http://dx.doi.org/10.1002/anie.202116672

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