Cargando…
Id3 expression identifies CD4(+) memory Th1 cells
Memory CD4(+) T cells play a pivotal role in mediating long-term protective immunity, positioning them as an important target in vaccine development. However, multiple functionally distinct helper CD4(+) T-cell subsets can arise in response to a single invading pathogen, complicating the identificat...
Autores principales: | Shaw, Laura A., Deng, Tianda Z., Omilusik, Kyla D., Takehara, Kennidy K., Nguyen, Quynh P., Goldrath, Ananda W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303986/ https://www.ncbi.nlm.nih.gov/pubmed/35858332 http://dx.doi.org/10.1073/pnas.2204254119 |
Ejemplares similares
-
Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8(+) T cells
por: Omilusik, Kyla D., et al.
Publicado: (2018) -
Id2 reinforces T(H)1 cell differentiation and inhibits E2A to repress T(FH) cell differentiation
por: Shaw, Laura A., et al.
Publicado: (2016) -
Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8(+) T cells
por: Delpoux, Arnaud, et al.
Publicado: (2018) -
Systems-level identification of key transcription factors in immune cell specification
por: Liu, Cong, et al.
Publicado: (2022) -
Transcriptional repressor ZEB2 promotes terminal differentiation of CD8(+) effector and memory T cell populations during infection
por: Omilusik, Kyla D., et al.
Publicado: (2015)