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Apoptotic caspases suppress an MDA5-driven IFN response during productive replication of human papillomavirus type 31

Human papillomaviruses (HPVs) infect the basal proliferating cells of the stratified epithelium, but the productive phase of the life cycle (consisting of viral genome amplification, late gene expression, and virion assembly) is restricted to the highly differentiated suprabasal cells. While much is...

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Detalles Bibliográficos
Autores principales: Huang, Ning, Groover, Des’ree, Damania, Blossom, Moody, Cary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303994/
https://www.ncbi.nlm.nih.gov/pubmed/35858339
http://dx.doi.org/10.1073/pnas.2200206119