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Structural basis and molecular mechanism of biased GPBAR signaling in regulating NSCLC cell growth via YAP activity
The G protein–coupled bile acid receptor (GPBAR) is the membrane receptor for bile acids and a driving force of the liver–bile acid–microbiota–organ axis to regulate metabolism and other pathophysiological processes. Although GPBAR is an important therapeutic target for a spectrum of metabolic and n...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303995/ https://www.ncbi.nlm.nih.gov/pubmed/35858343 http://dx.doi.org/10.1073/pnas.2117054119 |