Structural basis and molecular mechanism of biased GPBAR signaling in regulating NSCLC cell growth via YAP activity

The G protein–coupled bile acid receptor (GPBAR) is the membrane receptor for bile acids and a driving force of the liver–bile acid–microbiota–organ axis to regulate metabolism and other pathophysiological processes. Although GPBAR is an important therapeutic target for a spectrum of metabolic and n...

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Detalles Bibliográficos
Autores principales: Ma, Lijuan, Yang, Fan, Wu, Xiang, Mao, Chunyou, Guo, Lulu, Miao, Tianshu, Zang, Shao-Kun, Jiang, Xiaoyu, Shen, Dan-Dan, Wei, Tianhui, Zhou, Hengxing, Wei, Qin, Li, Shiyang, Shu, Qiang, Feng, Shiqing, Jiang, Changtao, Chu, Bo, Du, Lutao, Sun, Jin-Peng, Yu, Xiao, Zhang, Yan, Zhang, Pengju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303995/
https://www.ncbi.nlm.nih.gov/pubmed/35858343
http://dx.doi.org/10.1073/pnas.2117054119

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