Cargando…

Nosocomial COVID-19. Prospective study in a referral hospital

BACKGROUND AND OBJECTIVE: The objective was to describe the clinical characteristics and prognosis of patients with nosocomial SARS-CoV-2 infection. METHODS: An observational and prospective study was performed in a referral hospital. We included all adult patients diagnosed with nosocomial SARS-CoV...

Descripción completa

Detalles Bibliográficos
Autores principales: Escolà-Vergé, Laura, Borràs-Bermejo, Blanca, Los-Arcos, Ibai, Esperalba, Juliana, Ferrer, Carmen, Fernández-Hidalgo, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier España, S.L.U. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304152/
https://www.ncbi.nlm.nih.gov/pubmed/35891675
http://dx.doi.org/10.1016/j.medcle.2021.07.025
_version_ 1784752037277204480
author Escolà-Vergé, Laura
Borràs-Bermejo, Blanca
Los-Arcos, Ibai
Esperalba, Juliana
Ferrer, Carmen
Fernández-Hidalgo, Nuria
author_facet Escolà-Vergé, Laura
Borràs-Bermejo, Blanca
Los-Arcos, Ibai
Esperalba, Juliana
Ferrer, Carmen
Fernández-Hidalgo, Nuria
author_sort Escolà-Vergé, Laura
collection PubMed
description BACKGROUND AND OBJECTIVE: The objective was to describe the clinical characteristics and prognosis of patients with nosocomial SARS-CoV-2 infection. METHODS: An observational and prospective study was performed in a referral hospital. We included all adult patients diagnosed with nosocomial SARS-CoV-2 infection in October 2020. Nosocomial infection was defined as a negative PCR for SARS-CoV-2 on admission and a positive PCR after 7 days of hospitalization. RESULTS: We included 66 cases of nosocomial SARS-CoV-2 infection: 39 (59%) men, median age at diagnosis was 74.5 years (IQR 56.8–83.1) and median Charlson comorbidity index was 3 points (IQR 1–5). Twenty-seven (41%) developed pneumonia and 13 (20%) died during admission. Mortality at 28 days was 33% (22 patients). Mortality at 28 days in the 242 patients with community-acquired SARS-CoV-2 infection who were hospitalized during the same period was 10%. CONCLUSIONS: Preventive measures and early detection of nosocomial outbreaks of COVID-19 should be prioritized to minimize the negative impact of this infection.
format Online
Article
Text
id pubmed-9304152
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier España, S.L.U.
record_format MEDLINE/PubMed
spelling pubmed-93041522022-07-22 Nosocomial COVID-19. Prospective study in a referral hospital Escolà-Vergé, Laura Borràs-Bermejo, Blanca Los-Arcos, Ibai Esperalba, Juliana Ferrer, Carmen Fernández-Hidalgo, Nuria Med Clin (Engl Ed) Brief Report BACKGROUND AND OBJECTIVE: The objective was to describe the clinical characteristics and prognosis of patients with nosocomial SARS-CoV-2 infection. METHODS: An observational and prospective study was performed in a referral hospital. We included all adult patients diagnosed with nosocomial SARS-CoV-2 infection in October 2020. Nosocomial infection was defined as a negative PCR for SARS-CoV-2 on admission and a positive PCR after 7 days of hospitalization. RESULTS: We included 66 cases of nosocomial SARS-CoV-2 infection: 39 (59%) men, median age at diagnosis was 74.5 years (IQR 56.8–83.1) and median Charlson comorbidity index was 3 points (IQR 1–5). Twenty-seven (41%) developed pneumonia and 13 (20%) died during admission. Mortality at 28 days was 33% (22 patients). Mortality at 28 days in the 242 patients with community-acquired SARS-CoV-2 infection who were hospitalized during the same period was 10%. CONCLUSIONS: Preventive measures and early detection of nosocomial outbreaks of COVID-19 should be prioritized to minimize the negative impact of this infection. Elsevier España, S.L.U. 2022-08-12 2022-07-22 /pmc/articles/PMC9304152/ /pubmed/35891675 http://dx.doi.org/10.1016/j.medcle.2021.07.025 Text en © 2021 Elsevier España, S.L.U. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Report
Escolà-Vergé, Laura
Borràs-Bermejo, Blanca
Los-Arcos, Ibai
Esperalba, Juliana
Ferrer, Carmen
Fernández-Hidalgo, Nuria
Nosocomial COVID-19. Prospective study in a referral hospital
title Nosocomial COVID-19. Prospective study in a referral hospital
title_full Nosocomial COVID-19. Prospective study in a referral hospital
title_fullStr Nosocomial COVID-19. Prospective study in a referral hospital
title_full_unstemmed Nosocomial COVID-19. Prospective study in a referral hospital
title_short Nosocomial COVID-19. Prospective study in a referral hospital
title_sort nosocomial covid-19. prospective study in a referral hospital
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304152/
https://www.ncbi.nlm.nih.gov/pubmed/35891675
http://dx.doi.org/10.1016/j.medcle.2021.07.025
work_keys_str_mv AT escolavergelaura nosocomialcovid19prospectivestudyinareferralhospital
AT borrasbermejoblanca nosocomialcovid19prospectivestudyinareferralhospital
AT losarcosibai nosocomialcovid19prospectivestudyinareferralhospital
AT esperalbajuliana nosocomialcovid19prospectivestudyinareferralhospital
AT ferrercarmen nosocomialcovid19prospectivestudyinareferralhospital
AT fernandezhidalgonuria nosocomialcovid19prospectivestudyinareferralhospital