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MUL1‐RING recruits the substrate, p53‐TAD as a complex with UBE2D2–UB conjugate

The RING domain of MUL1 (RING(MUL1)) alone mediates ubiquitylation of the p53‐transactivation domain (TAD(p53)). To elucidate the mechanism underlying the simultaneous recruitment of UBE2D2 and the substrate TAD(p53) by RING(MUL1), we determined the complex structure of RING(MUL1):UBE2D2 and studied...

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Detalles Bibliográficos
Autores principales:	Lee, Min‐Sung, Lee, Sang‐Ok, Choi, Joonhyeok, Ryu, Minju, Lee, Mi‐Kyung, Kim, Ji‐Hun, Hwang, Eunha, Lee, Chong‐Kil, Chi, Seung‐Wook, Ryu, Kyoung‐Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304225/ https://www.ncbi.nlm.nih.gov/pubmed/35048531 http://dx.doi.org/10.1111/febs.16360

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