A population of naive‐like CD4(+) T cells stably polarized to the T(H)1 lineage

T‐bet is the lineage‐specifying transcription factor for CD4(+) T(H)1 cells. T‐bet has also been found in other CD4(+) T cell subsets, including T(H)17 cells and Treg, where it modulates their functional characteristics. However, we lack information on when and where T‐bet is expressed during T cell...

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Detalles Bibliográficos
Autores principales: Lo, Jonathan W., de Mucha, Maria Vila, Henderson, Stephen, Roberts, Luke B., Constable, Laura E., Garrido‐Mesa, Natividad, Hertweck, Arnulf, Stolarczyk, Emilie, Houlder, Emma L., Jackson, Ian, MacDonald, Andrew S., Powell, Nick, Neves, Joana F., Howard, Jane K., Jenner, Richard G., Lord, Graham M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Adaptive immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304323/
https://www.ncbi.nlm.nih.gov/pubmed/35092032
http://dx.doi.org/10.1002/eji.202149228

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