SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction

Defective execution of proteases and protease inhibitors that mediate abnormal signaling cascades is emerging as a key contributor to skin diseases, such as psoriasis. SerpinB7 is identified as a skin-specific endogenous protease inhibitor, but the role and underlying mechanism in psoriasis are poor...

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Detalles Bibliográficos
Autores principales: Zheng, Huaping, Gu, Linna, Zhao, Fulei, Zhang, Chen, Wang, Zhen, Zhou, Hong, Hu, Zhonglan, Wei, Xiaoqiong, Liu, Xiao, Luo, Feng, Zeng, Fanlian, Zhao, Qixiang, Hao, Yan, Hu, Yawen, Wang, Xiaoyan, Hu, Jing, Yu, Jiadong, Wu, Wenling, Zhou, Yifan, Zhou, Pei, Yue, Chengcheng, Huang, Nongyu, Cui, Kaijun, Li, Wei, Li, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304369/
https://www.ncbi.nlm.nih.gov/pubmed/35864103
http://dx.doi.org/10.1038/s41419-022-05045-8

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