Engineered biomimetic nanoparticles achieve targeted delivery and efficient metabolism-based synergistic therapy against glioblastoma

Glioblastoma multiforme (GBM) is an aggressive brain cancer with a poor prognosis and few treatment options. Here, building on the observation of elevated lactate (LA) in resected GBM, we develop biomimetic therapeutic nanoparticles (NPs) that deliver agents for LA metabolism-based synergistic thera...

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Detalles Bibliográficos
Autores principales: Lu, Guihong, Wang, Xiaojun, Li, Feng, Wang, Shuang, Zhao, Jiawei, Wang, Jinyi, Liu, Jing, Lyu, Chengliang, Ye, Peng, Tan, Hui, Li, Weiping, Ma, Guanghui, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304377/
https://www.ncbi.nlm.nih.gov/pubmed/35864093
http://dx.doi.org/10.1038/s41467-022-31799-y

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