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Evaluating the role of common risk variation in the recurrence risk of schizophrenia in multiplex schizophrenia families

Multiplex families have higher recurrence risk of schizophrenia compared to the families of sporadic cases, but the source of this increased recurrence risk is unknown. We used schizophrenia genome-wide association study data (N = 156,509) to construct polygenic risk scores (PRS) in 1005 individuals...

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Detalles Bibliográficos
Autores principales:	Ahangari, Mohammad, Gentry, Amanda E., Nguyen, Tan-Hoang, Kirkpatrick, Robert, Verrelli, Brian C., Bacanu, Silviu-Alin, Kendler, Kenneth S., Webb, Bradley T., Riley, Brien P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304393/ https://www.ncbi.nlm.nih.gov/pubmed/35864105 http://dx.doi.org/10.1038/s41398-022-02060-3

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