Cargando…

Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex

HNRNPU encodes the heterogeneous nuclear ribonucleoprotein U, which participates in RNA splicing and chromatin organization. Microdeletions in the 1q44 locus encompassing HNRNPU and other genes and point mutations in HNRNPU cause brain disorders, including early-onset seizures and severe intellectua...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sapir, Tamar, Kshirsagar, Aditya, Gorelik, Anna, Olender, Tsviya, Porat, Ziv, Scheffer, Ingrid E., Goldstein, David B., Devinsky, Orrin, Reiner, Orly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304408/ https://www.ncbi.nlm.nih.gov/pubmed/35864088 http://dx.doi.org/10.1038/s41467-022-31752-z

Ejemplares similares

Developmental activities of the complement pathway in migrating neurons
por: Gorelik, Anna, et al.
Publicado: (2017)

Evidence of shared transcriptomic dysregulation of HNRNPU-related disorder between human organoids and embryonic mice
por: Ressler, Andrew K., et al.
Publicado: (2022)

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways
por: Kshirsagar, Aditya, et al.
Publicado: (2023)

Gene trapping: An antibody-dependent approach for verifying integration in your favorite gene
por: Gorelik, Anna, et al.
Publicado: (2008)

Complement C3 Affects Rac1 Activity in the Developing Brain
por: Gorelik, Anna, et al.
Publicado: (2018)

Serping1/C1 Inhibitor Affects Cortical Development in a Cell Autonomous and Non-cell Autonomous Manner
por: Gorelik, Anna, et al.
Publicado: (2017)

Interplay of LIS1 and MeCP2: Interactions and Implications With the Neurodevelopmental Disorders Lissencephaly and Rett Syndrome
por: Keidar, Liraz, et al.
Publicado: (2019)

Targeting HNRNPU to overcome cisplatin resistance in bladder cancer
por: Shi, Zhen-duo, et al.
Publicado: (2022)

Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate
por: Parichha, Arpan, et al.
Publicado: (2022)

Germline pathogenic variants in HNRNPU are associated with alterations in blood methylome
por: Lee, Sunwoo, et al.
Publicado: (2023)

Using multi-organ culture systems to study Parkinson’s disease
por: Reiner, Orly, et al.
Publicado: (2020)

Reversible Cysteine Acylation Regulates the Activity of Human Palmitoyl-Protein Thioesterase 1 (PPT1)
por: Segal-Salto, Michal, et al.
Publicado: (2016)

Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency
por: Dugger, Sarah A., et al.
Publicado: (2023)

Brain Organization and Human Diseases
por: Sapir, Tamar, et al.
Publicado: (2022)

Expanding the phenotype of HNRNPU ‐related neurodevelopmental disorder with emphasis on seizure phenotype and review of literature
por: Taylor, James, et al.
Publicado: (2022)

Microglial Pten safeguards postnatal integrity of the cortex and sociability
por: Zhou, Xing, et al.
Publicado: (2022)

Partitioning of ribonucleoprotein complexes from the cellular actin cortex
por: Angert, Isaac, et al.
Publicado: (2022)

Ancient genomic architecture for mammalian olfactory receptor clusters
por: Aloni, Ronny, et al.
Publicado: (2006)

Sedentary Behavior Impacts on the Epigenome and Transcriptome: Lessons from Muscle Inactivation in Drosophila Larvae
por: Brener, Avivit, et al.
Publicado: (2023)

Expression Profiling Identifies the Noncoding Processed Transcript of HNRNPU with Proliferative Properties in Pancreatic Ductal Adenocarcinoma
por: Sutaria, Dhruvitkumar S., et al.
Publicado: (2017)

The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes
por: Fan, Hui, et al.
Publicado: (2018)

Analysis of the nucleocytoplasmic shuttling RNA-binding protein HNRNPU using optimized HITS-CLIP method
por: Yugami, Masato, et al.
Publicado: (2020)

Update on the olfactory receptor (OR) gene superfamily
por: Olender, Tsviya, et al.
Publicado: (2008)

U1 small nuclear ribonucleoprotein studied by in vitro assembly
Publicado: (1983)

Human Brain Organoids on a Chip Reveal the Physics of Folding
por: Karzbrun, Eyal, et al.
Publicado: (2018)

Use of RNA Interference by In Utero Electroporation to Study Cortical Development: The Example of the Doublecortin Superfamily
por: Reiner, Orly, et al.
Publicado: (2012)

CDC20-Mediated hnRNPU Ubiquitination Regulates Chromatin Condensation and Anti-Cancer Drug Response
por: Wavelet-Vermuse, Cindy, et al.
Publicado: (2022)

HNRNPU promotes the progression of triple-negative breast cancer via RNA transcription and alternative splicing mechanisms
por: Han, Bo-yue, et al.
Publicado: (2022)

Common peptides shed light on evolution of Olfactory Receptors
por: Gottlieb, Assaf, et al.
Publicado: (2009)

A new function for the serine protease HtrA2 in controlling radiation‐induced senescence in cancer cells
por: Hammer, Liat, et al.
Publicado: (2022)

Non-cell autonomous and non-catalytic activities of ATX in the developing brain
por: Greenman, Raanan, et al.
Publicado: (2015)

Safeguards
por: Ahonen, Pasi, et al.
Publicado: (2008)

Learning hierarchical sequence representations across human cortex and hippocampus
por: Henin, Simon, et al.
Publicado: (2021)

Seizure Clusters: Morbidity and Mortality
por: Bauman, Kristie, et al.
Publicado: (2021)

Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly
Publicado: (1984)

Deficiency of the Heterogeneous Nuclear Ribonucleoprotein U locus leads to delayed hindbrain neurogenesis
por: Mastropasqua, Francesca, et al.
Publicado: (2023)

Mixture Coding and Segmentation in the Anterior Piriform Cortex
por: Penker, Sapir, et al.
Publicado: (2020)

A unified nomenclature for vertebrate olfactory receptors
por: Olender, Tsviya, et al.
Publicado: (2020)

Autoimmune response to U1 small nuclear ribonucleoprotein (U1 snRNP) associated with cytomegalovirus infection
por: Newkirk, Marianna M, et al.
Publicado: (2001)

The Interactome of Palmitoyl-Protein Thioesterase 1 (PPT1) Affects Neuronal Morphology and Function
por: Sapir, Tamar, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_k4n7qvv2a6e3rdnodibcgrg9bi