A phosphite-based screening platform for identification of enzymes favoring nonnatural cofactors

Enzymes with dedicated cofactor preference are essential for advanced biocatalysis and biomanufacturing, especially when employing nonnatural nicotinamide cofactors in redox reactions. However, directed evolution of an enzyme to switch its cofactor preference is often hindered by the lack of efficie...

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Detalles Bibliográficos
Autores principales: Liu, Yuxue, Li, Zhuoya, Guo, Xiaojia, Wang, Xueying, Zhao, Zongbao K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304416/
https://www.ncbi.nlm.nih.gov/pubmed/35864126
http://dx.doi.org/10.1038/s41598-022-16599-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304416/
https://www.ncbi.nlm.nih.gov/pubmed/35864126
http://dx.doi.org/10.1038/s41598-022-16599-0

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