Cargando…

Inferring the underlying multivariate structure from bivariate networks with highly correlated nodes

Complex systems are often described mathematically as networks. Inferring the actual interactions from observed dynamics of the nodes of the networks is a challenging inverse task. It is crucial to distinguish direct and indirect interactions to allow for a robust identification of the underlying ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Loske, Philipp, Schelter, Bjoern O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304421/
https://www.ncbi.nlm.nih.gov/pubmed/35864116
http://dx.doi.org/10.1038/s41598-022-16296-y
_version_ 1784752100272504832
author Loske, Philipp
Schelter, Bjoern O.
author_facet Loske, Philipp
Schelter, Bjoern O.
author_sort Loske, Philipp
collection PubMed
description Complex systems are often described mathematically as networks. Inferring the actual interactions from observed dynamics of the nodes of the networks is a challenging inverse task. It is crucial to distinguish direct and indirect interactions to allow for a robust identification of the underlying network. If strong and weak links are simultaneously present in the observed network, typical multivariate approaches to address this challenge fail. By means of correlation and partial correlation, we illustrate the challenges that arise and demonstrate how to overcome these. The challenge of strong and weak links translates into ill-conditioned matrices that need to be inverted to obtain the partial correlations, and therefore the correct network topology. Our novel procedure enables robust identification of multivariate network topologies in the presence of highly correlated processes. In applications, this is crucial to avoid erroneous conclusions about network structures and characteristics. Our novel approach applies to other types of interaction measures between processes in a network.
format Online
Article
Text
id pubmed-9304421
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-93044212022-07-23 Inferring the underlying multivariate structure from bivariate networks with highly correlated nodes Loske, Philipp Schelter, Bjoern O. Sci Rep Article Complex systems are often described mathematically as networks. Inferring the actual interactions from observed dynamics of the nodes of the networks is a challenging inverse task. It is crucial to distinguish direct and indirect interactions to allow for a robust identification of the underlying network. If strong and weak links are simultaneously present in the observed network, typical multivariate approaches to address this challenge fail. By means of correlation and partial correlation, we illustrate the challenges that arise and demonstrate how to overcome these. The challenge of strong and weak links translates into ill-conditioned matrices that need to be inverted to obtain the partial correlations, and therefore the correct network topology. Our novel procedure enables robust identification of multivariate network topologies in the presence of highly correlated processes. In applications, this is crucial to avoid erroneous conclusions about network structures and characteristics. Our novel approach applies to other types of interaction measures between processes in a network. Nature Publishing Group UK 2022-07-21 /pmc/articles/PMC9304421/ /pubmed/35864116 http://dx.doi.org/10.1038/s41598-022-16296-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Loske, Philipp
Schelter, Bjoern O.
Inferring the underlying multivariate structure from bivariate networks with highly correlated nodes
title Inferring the underlying multivariate structure from bivariate networks with highly correlated nodes
title_full Inferring the underlying multivariate structure from bivariate networks with highly correlated nodes
title_fullStr Inferring the underlying multivariate structure from bivariate networks with highly correlated nodes
title_full_unstemmed Inferring the underlying multivariate structure from bivariate networks with highly correlated nodes
title_short Inferring the underlying multivariate structure from bivariate networks with highly correlated nodes
title_sort inferring the underlying multivariate structure from bivariate networks with highly correlated nodes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304421/
https://www.ncbi.nlm.nih.gov/pubmed/35864116
http://dx.doi.org/10.1038/s41598-022-16296-y
work_keys_str_mv AT loskephilipp inferringtheunderlyingmultivariatestructurefrombivariatenetworkswithhighlycorrelatednodes
AT schelterbjoerno inferringtheunderlyingmultivariatestructurefrombivariatenetworkswithhighlycorrelatednodes