Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors

A lentiviral vector (LV) pseudotype derived from the fusion (F) and hemagglutinin-neuraminidase (HN) glycoproteins of a murine respirovirus (Sendai virus) facilitates efficient targeting of murine lung in vivo. Since targeting of the human lung will depend upon the availability and distribution of r...

Descripción completa

Detalles Bibliográficos
Autores principales: Munday, Rosie J., Coradin, Tiziana, Nimmo, Rachael, Lad, Yatish, Hyde, Stephen C., Mitrophanos, Kyriacos, Gill, Deborah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304433/
https://www.ncbi.nlm.nih.gov/pubmed/35892086
http://dx.doi.org/10.1016/j.omtm.2022.07.002

Ejemplares similares

Ejemplares similares