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The ICOS–ICOSL pathway tunes thymic selection

Negative selection of developing T cells plays a significant role in T‐cell tolerance to self‐antigen. This process relies on thymic antigen‐presenting cells which express both self‐antigens and cosignaling molecules. Inducible T‐cell costimulator (ICOS) belongs to the CD28 family of cosignaling mol...

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Detalles Bibliográficos
Autores principales:	Dong, Mengqi, Chang, Jinsam, Lebel, Marie‐Ève, Gervais, Noémie, Fournier, Marilaine, Mallet Gauthier, Ève, Suh, Woong‐Kyung, Melichar, Heather J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304562/ https://www.ncbi.nlm.nih.gov/pubmed/34962663 http://dx.doi.org/10.1111/imcb.12520

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