HIRA Supports Hepatitis B Virus Minichromosome Establishment and Transcriptional Activity in Infected Hepatocytes

BACKGROUND & AIMS: Upon hepatitis B virus (HBV) infection, partially double-stranded viral DNA converts into a covalently closed circular chromatinized episomal structure (cccDNA). This form represents the long-lived genomic reservoir responsible for viral persistence in the infected liver. Alth...

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Detalles Bibliográficos
Autores principales: Locatelli, Maëlle, Quivy, Jean-Pierre, Chapus, Fleur, Michelet, Maud, Fresquet, Judith, Maadadi, Sarah, Aberkane, Amel Neila, Diederichs, Audrey, Lucifora, Julie, Rivoire, Michel, Almouzni, Geneviève, Testoni, Barbara, Zoulim, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304598/
https://www.ncbi.nlm.nih.gov/pubmed/35643233
http://dx.doi.org/10.1016/j.jcmgh.2022.05.007

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