Targeting Multiple End Organs in Lupus and Other Systemic Rheumatic Diseases by Inhibiting Bruton’s Tyrosine Kinase

Bruton tyrosine kinase (Btk) plays a vital role in activating and differentiating B-cells and regulating signaling in myeloid cells. Indeed, the potential use of Btk inhibitors in preventing lupus has been reported. Here, we extend these observations to 4 additional models of end-organ inflammation:...

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Detalles Bibliográficos
Autores principales: Du, Yong, Lei, Ling, Ding, Huihua, Chen, Yanping, Pathak, Simanta, Hicks, John, Tran, Phuongthy T., Wu, Minghua, Chang, Betty, Wirtz, Uwe, Mohan, Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304663/
https://www.ncbi.nlm.nih.gov/pubmed/35874767
http://dx.doi.org/10.3389/fimmu.2022.893899

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