Using population-scale transcriptomic and genomic data to map 3′ UTR alternative polyadenylation quantitative trait loci

3′ UTR alternative polyadenylation (APA) quantitative trait loci (3′aQTL) can explain approximately 16.1% of trait-associated non-coding variants and is largely distinct from other molecular QTLs. Here, we describe a bioinformatic protocol for identifying 3′aQTLs through standard RNA-seq and matched...

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Detalles Bibliográficos
Autores principales: Zou, Xudong, Ding, Ruofan, Chen, Wenyan, Wang, Gao, Cheng, Shumin, Wang, Qin, Li, Wei, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304671/
https://www.ncbi.nlm.nih.gov/pubmed/35874472
http://dx.doi.org/10.1016/j.xpro.2022.101566

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