Inhibition of NLRP3-mediated crosstalk between hepatocytes and liver macrophages by geniposidic acid alleviates cholestatic liver inflammatory injury

The excessive accumulation of bile acids (BA) in hepatocytes can trigger inflammatory response and recruit macrophages, thereby accelerating cholestatic liver injury. The crosstalk between hepatocytes and macrophages has been recently implicated in the pathogenesis of cholestasis; however, the under...

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Detalles Bibliográficos
Autores principales: Song, Meng, Chen, Zijun, Qiu, Ruian, Zhi, Tingwei, Xie, Wenmin, Zhou, Yingya, Luo, Nachuan, Fuqian Chen, Liu, Fang, Shen, Chuangpeng, Lin, Sheng, Zhang, Fengxue, Gao, Yong, Liu, Changhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304672/
https://www.ncbi.nlm.nih.gov/pubmed/35868156
http://dx.doi.org/10.1016/j.redox.2022.102404

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