Mitochondria-targeted anti-oxidant AntiOxCIN(4) improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems

Non-alcoholic fatty liver disease (NAFLD) is a health concern affecting 24% of the population worldwide. Although the pathophysiologic mechanisms underlying disease are not fully clarified, mitochondrial dysfunction and oxidative stress are key players in disease progression. Consequently, efforts t...

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Detalles Bibliográficos
Autores principales: Amorim, Ricardo, Simões, Inês C.M., Teixeira, José, Cagide, Fernando, Potes, Yaiza, Soares, Pedro, Carvalho, Adriana, Tavares, Ludgero C., Benfeito, Sofia, Pereira, Susana P., Simões, Rui F., Karkucinska-Wieckowska, Agnieszka, Viegas, Ivan, Szymanska, Sylwia, Dąbrowski, Michał, Janikiewicz, Justyna, Cunha-Oliveira, Teresa, Dobrzyń, Agnieszka, Jones, John G., Borges, Fernanda, Wieckowski, Mariusz R., Oliveira, Paulo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304680/
https://www.ncbi.nlm.nih.gov/pubmed/35863265
http://dx.doi.org/10.1016/j.redox.2022.102400

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