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The Majority of United States Citizens With Cancer do not Have Access to Carbon Ion Radiotherapy
As of December 31, 2020, there were 12 facilities located in Asia and Europe which were treating cancer patients with carbon ion radiotherapy (CIRT). Between June 1994 and December 2020, 37,548 patients were treated with CIRT worldwide. Fifteen of these patients were United States (U.S.) citizens. U...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304691/ https://www.ncbi.nlm.nih.gov/pubmed/35875126 http://dx.doi.org/10.3389/fonc.2022.954747 |
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author | Foote, Robert L. Tsujii, Hirohiko Imai, Reiko Tsuji, Hiroshi Hug, Eugen B. Kanai, Tatsuaki Lu, Jiade J. Debus, Juergen Engenhart-Cabillic, Rita Mahajan, Anita |
author_facet | Foote, Robert L. Tsujii, Hirohiko Imai, Reiko Tsuji, Hiroshi Hug, Eugen B. Kanai, Tatsuaki Lu, Jiade J. Debus, Juergen Engenhart-Cabillic, Rita Mahajan, Anita |
author_sort | Foote, Robert L. |
collection | PubMed |
description | As of December 31, 2020, there were 12 facilities located in Asia and Europe which were treating cancer patients with carbon ion radiotherapy (CIRT). Between June 1994 and December 2020, 37,548 patients were treated with CIRT worldwide. Fifteen of these patients were United States (U.S.) citizens. Using the Surveillance, Epidemiology, and End Results cancer statistics database, the Mayo Clinic in Rochester, MN has conservatively estimated that there are approximately 44,340 people diagnosed each year in the U.S. with malignancies that would benefit from treatment with CIRT. The absence of CIRT facilities in the U.S. not only limits access to CIRT for cancer care but also prevents inclusion of U.S. citizens in phase III clinical trials that will determine the comparative effectiveness and cost effectiveness of CIRT for a variety of malignancies for FDA approval and insurance coverage. Past and present phase III clinical trials have not been able to enroll U.S. citizens due to their unwillingness or inability to travel abroad for CIRT for an extended period. These barriers could be overcome with a limited number of CIRT facilities in the U.S. |
format | Online Article Text |
id | pubmed-9304691 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93046912022-07-23 The Majority of United States Citizens With Cancer do not Have Access to Carbon Ion Radiotherapy Foote, Robert L. Tsujii, Hirohiko Imai, Reiko Tsuji, Hiroshi Hug, Eugen B. Kanai, Tatsuaki Lu, Jiade J. Debus, Juergen Engenhart-Cabillic, Rita Mahajan, Anita Front Oncol Oncology As of December 31, 2020, there were 12 facilities located in Asia and Europe which were treating cancer patients with carbon ion radiotherapy (CIRT). Between June 1994 and December 2020, 37,548 patients were treated with CIRT worldwide. Fifteen of these patients were United States (U.S.) citizens. Using the Surveillance, Epidemiology, and End Results cancer statistics database, the Mayo Clinic in Rochester, MN has conservatively estimated that there are approximately 44,340 people diagnosed each year in the U.S. with malignancies that would benefit from treatment with CIRT. The absence of CIRT facilities in the U.S. not only limits access to CIRT for cancer care but also prevents inclusion of U.S. citizens in phase III clinical trials that will determine the comparative effectiveness and cost effectiveness of CIRT for a variety of malignancies for FDA approval and insurance coverage. Past and present phase III clinical trials have not been able to enroll U.S. citizens due to their unwillingness or inability to travel abroad for CIRT for an extended period. These barriers could be overcome with a limited number of CIRT facilities in the U.S. Frontiers Media S.A. 2022-07-08 /pmc/articles/PMC9304691/ /pubmed/35875126 http://dx.doi.org/10.3389/fonc.2022.954747 Text en Copyright © 2022 Foote, Tsujii, Imai, Tsuji, Hug, Kanai, Lu, Debus, Engenhart-Cabillic and Mahajan https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Foote, Robert L. Tsujii, Hirohiko Imai, Reiko Tsuji, Hiroshi Hug, Eugen B. Kanai, Tatsuaki Lu, Jiade J. Debus, Juergen Engenhart-Cabillic, Rita Mahajan, Anita The Majority of United States Citizens With Cancer do not Have Access to Carbon Ion Radiotherapy |
title | The Majority of United States Citizens With Cancer do not Have Access to Carbon Ion Radiotherapy |
title_full | The Majority of United States Citizens With Cancer do not Have Access to Carbon Ion Radiotherapy |
title_fullStr | The Majority of United States Citizens With Cancer do not Have Access to Carbon Ion Radiotherapy |
title_full_unstemmed | The Majority of United States Citizens With Cancer do not Have Access to Carbon Ion Radiotherapy |
title_short | The Majority of United States Citizens With Cancer do not Have Access to Carbon Ion Radiotherapy |
title_sort | majority of united states citizens with cancer do not have access to carbon ion radiotherapy |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304691/ https://www.ncbi.nlm.nih.gov/pubmed/35875126 http://dx.doi.org/10.3389/fonc.2022.954747 |
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