Small Peptide Derivatives Within the Carbohydrate Recognition Domain of SP-A2 Modulate Asthma Outcomes in Mouse Models and Human Cells

Surfactant Protein-A (SP-A) is an innate immune modulator that regulates a variety of pulmonary host defense functions. We have shown that SP-A is dysfunctional in asthma, which could be partly due to genetic heterogeneity. In mouse models and primary bronchial epithelial cells from asthmatic partic...

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Detalles Bibliográficos
Autores principales: Francisco, Dave, Wang, Ying, Marshall, Craig, Conway, Michelle, Addison, Kenneth J., Billheimer, Dean, Kimura, Hiroki, Numata, Mari, Chu, Hong W., Voelker, Dennis R., Kraft, Monica, Ledford, Julie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304716/
https://www.ncbi.nlm.nih.gov/pubmed/35874703
http://dx.doi.org/10.3389/fimmu.2022.900022

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