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Modeling Parkinson's disease‐related symptoms in alpha‐synuclein overexpressing mice
BACKGROUND: Intracellular deposition of alpha‐synuclein (α‐syn) as Lewy bodies and Lewy neurites is a central event in the pathogenesis of Parkinson's disease (PD) and other α‐synucleinopathies. Transgenic mouse models overexpressing human α‐syn, are useful research tools in preclinical studies...
Autores principales: | Aniszewska, Agata, Bergström, Joakim, Ingelsson, Martin, Ekmark‐Lewén, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304846/ https://www.ncbi.nlm.nih.gov/pubmed/35652155 http://dx.doi.org/10.1002/brb3.2628 |
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