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Modeling Parkinson's disease‐related symptoms in alpha‐synuclein overexpressing mice

BACKGROUND: Intracellular deposition of alpha‐synuclein (α‐syn) as Lewy bodies and Lewy neurites is a central event in the pathogenesis of Parkinson's disease (PD) and other α‐synucleinopathies. Transgenic mouse models overexpressing human α‐syn, are useful research tools in preclinical studies...

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Detalles Bibliográficos
Autores principales: Aniszewska, Agata, Bergström, Joakim, Ingelsson, Martin, Ekmark‐Lewén, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304846/
https://www.ncbi.nlm.nih.gov/pubmed/35652155
http://dx.doi.org/10.1002/brb3.2628

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