Cargando…

Association Between Serum Carnosinase Concentration and Activity and Renal Function Impairment in a Type-2 Diabetes Cohort

Introduction: Genetic studies have identified associations of carnosinase 1 (CN1) polymorphisms with diabetic kidney disease (DKD). However, CN1 levels and activities have not been assessed as diagnostic or prognostic markers of DKD in cohorts of patients with type 2 diabetes (T2D). Methods: We esta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiu, Jiedong, Yard, Benito A., Krämer, Bernhard K., van Goor, Harry, van Dijk, Peter, Kannt, Aimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304884/ https://www.ncbi.nlm.nih.gov/pubmed/35873562 http://dx.doi.org/10.3389/fphar.2022.899057

Ejemplares similares

Human carnosinase 1 overexpression aggravates diabetes and renal impairment in BTBR(Ob/Ob) mice
por: Qiu, Jiedong, et al.
Publicado: (2020)

Serum Carnosinase-1 and Albuminuria Rather than the CNDP1 Genotype Correlate with Urinary Carnosinase-1 in Diabetic and Nondiabetic Patients with Chronic Kidney Disease
por: Rodriguez-Niño, Angelica, et al.
Publicado: (2019)

Correlation between serum carnosinase concentration and renal damage in diabetic nephropathy patients
por: Zhou, Zhou, et al.
Publicado: (2021)

Serum and urinary carnosinase-1 correlate with kidney function and inflammation
por: Zhang, Shiqi, et al.
Publicado: (2022)

Monoclonal Antibody RYSK173 Recognizes the Dinuclear Zn Center of Serum Carnosinase 1 (CN-1): Possible Consequences of Zn Binding for CN-1 Recognition by RYSK173
por: Zhang, Shiqi, et al.
Publicado: (2016)

Correction: Monoclonal Antibody RYSK173 Recognizes the Dinuclear Zn Center of Serum Carnosinase 1 (CN-1): Possible Consequences of Zn Binding for CN-1 Recognition by RYSK173
por: Zhang, Shiqi, et al.
Publicado: (2017)

N-Glycosylation of Carnosinase Influences Protein Secretion and Enzyme Activity: Implications for Hyperglycemia
por: Riedl, Eva, et al.
Publicado: (2010)

Carnosinases, Their Substrates and Diseases
por: Bellia, Francesco, et al.
Publicado: (2014)

Erythrocytes Prevent Degradation of Carnosine by Human Serum Carnosinase
por: Oppermann, Henry, et al.
Publicado: (2021)

Urinary Carnosinase-1 Excretion is Associated with Urinary Carnosine Depletion and Risk of Graft Failure in Kidney Transplant Recipients: Results of the TransplantLines Cohort Study
por: Rodriguez-Niño, Angelica, et al.
Publicado: (2021)

Brain type carnosinase in dementia: a pilot study
por: Balion, Cynthia M, et al.
Publicado: (2007)

Allosteric inhibition of carnosinase (CN1) by inducing a conformational shift
por: Peters, Verena, et al.
Publicado: (2017)

Binding Modes of Carnostatine, Homocarnosine, and Ophidine to Human Carnosinase 1
por: Toviwek, Borvornwat, et al.
Publicado: (2023)

Acute balenine supplementation in humans as a natural carnosinase-resistant alternative to carnosine
por: de Jager, Sarah, et al.
Publicado: (2023)

The Role of Gasotransmitters in Gut Peptide Actions
por: Verbeure, Wout, et al.
Publicado: (2021)

ET-CORM Mediated Vasorelaxation of Small Mesenteric Arteries: Involvement of Kv7 Potassium Channels
por: Zhang, Danfeng, et al.
Publicado: (2021)

Managing risks in drug discovery: reproducibility of published findings
por: Kannt, Aimo, et al.
Publicado: (2016)

Short-term variability of the human serum metabolome depending on nutritional and metabolic health status
por: Agueusop, Inoncent, et al.
Publicado: (2020)

Serum Creatinine and Serum Cystatin C are Both Relevant Renal Markers to Estimate Vancomycin Clearance in Critically Ill Neonates
por: Leroux, Stéphanie, et al.
Publicado: (2021)

Hypomagnesemia in persons with type 1 diabetes: associations with clinical parameters and oxidative stress
por: van Dijk, Peter R., et al.
Publicado: (2020)

Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet
por: Pfeffer, Tilman, et al.
Publicado: (2023)

Pharmacokinetics and Safety of Omadacycline in Subjects with Impaired Renal Function
por: Berg, Jolene K., et al.
Publicado: (2018)

Polymyxin B in Patients With Renal Impairment: Is It Necessary to Adjust Dose?
por: Nie, Ruifang, et al.
Publicado: (2022)

A polymorphism in the gene encoding carnosinase (CNDP1) as a predictor of mortality and progression from nephropathy to end-stage renal disease in type 1 diabetes mellitus
por: Alkhalaf, A., et al.
Publicado: (2010)

Influence of continuous renal replacement therapy on the plasma concentration of tigecycline in patients with septic shock: A prospective observational study
por: Huang, Fang, et al.
Publicado: (2023)

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance
por: Kannt, Aimo, et al.
Publicado: (2015)

Safety and pharmacokinetics of SPR206 in subjects with varying degrees of renal impairment
por: Bruss, Jon B., et al.
Publicado: (2023)

Cardiac Protection by Oral Sodium Thiosulfate in a Rat Model of L-NNA-Induced Heart Disease
por: Nguyen, Isabel T. N., et al.
Publicado: (2021)

Serum Concentrations of Cholinesterase Inhibitors in Patients With Alzheimer’s Dementia Are Frequently Below the Recommended Levels
por: Ortner, Marion, et al.
Publicado: (2020)

Hyperglycemia Does Not Affect Iron Mediated Toxicity of Cultured Endothelial and Renal Tubular Epithelial Cells: Influence of L-Carnosine
por: Zhang, Shiqi, et al.
Publicado: (2016)

Selective inhibitors of cardiac ADPR cyclase as novel anti-arrhythmic compounds
por: Kannt, Aimo, et al.
Publicado: (2012)

Physiologically based pharmacokinetic modeling of daptomycin dose optimization in pediatric patients with renal impairment
por: Ye, Lingling, et al.
Publicado: (2022)

Safety and Pharmacokinetics of Taniborbactam (VNRX-5133) with Cefepime in Subjects with Various Degrees of Renal Impairment
por: Dowell, James A., et al.
Publicado: (2022)

Dosage Strategy of Linezolid According to the Trough Concentration Target and Renal Function in Chinese Critically Ill Patients
por: Wu, Fan, et al.
Publicado: (2022)

Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men
por: Puiu, Andrei A., et al.
Publicado: (2019)

The CNDP1 (CTG)(5) Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration
por: Albrecht, Thomas, et al.
Publicado: (2017)

Changes in CD73, CD39 and CD26 expression on T-lymphocytes of ANCA-associated vasculitis patients suggest impairment in adenosine generation and turn-over
por: Kling, Lovis, et al.
Publicado: (2017)

Both LDL and HDL particle concentrations associate positively with an increased risk of developing microvascular complications in patients with type 2 diabetes: lost protection by HDL (Zodiac-63)
por: Bourgonje, Arno R., et al.
Publicado: (2023)

Role of Impaired Oxalate Homeostasis in Cardiovascular Disease in Patients With End-Stage Renal Disease: An Opinion Article
por: Stepanova, Natalia
Publicado: (2021)

Six years’ experience and trends of serum 25-hydroxy vitamin D concentration and the effect of vitamin D(3) consumption on these trends
por: Horváth, László, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9c7bq2lsidqnet643ovk0fr19p