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Targeting AKT-Dependent Regulation of Antioxidant Defense Sensitizes AKT-E17K Expressing Cancer Cells to Ionizing Radiation

Aberrant activation of the phosphatidyl-inositol-3-kinase/protein kinase B (AKT) pathway has clinical relevance to radiation resistance, but the underlying mechanisms are incompletely understood. Protection against reactive oxygen species (ROS) plays an emerging role in the regulation of cell surviv...

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Detalles Bibliográficos
Autores principales:	Goetting, Isabell, Larafa, Safa, Eul, Katharina, Kunin, Mikhail, Jakob, Burkhard, Matschke, Johann, Jendrossek, Verena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304891/ https://www.ncbi.nlm.nih.gov/pubmed/35875130 http://dx.doi.org/10.3389/fonc.2022.920017

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