Cargando…

An OGT-STAT5 Axis in Regulatory T Cells Controls Energy and Iron Metabolism

The immunosuppressive regulatory T (Treg) cells exert emerging effects on adipose tissue homeostasis and systemic metabolism. However, the metabolic regulation and effector mechanisms of Treg cells in coping with obesogenic insults are not fully understood. We have previously established an indispen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Zengdi, Salgado, Oscar C., Liu, Bing, Moazzami, Zahra, Hogquist, Kristin A., Farrar, Michael A., Ruan, Hai-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304952/ https://www.ncbi.nlm.nih.gov/pubmed/35874700 http://dx.doi.org/10.3389/fimmu.2022.874863

Ejemplares similares

Intestinal Epithelial STAT6 Activation Rescues the Defective Anti-Helminth Responses Caused by Ogt Deletion
por: Xiong, Xiwen, et al.
Publicado: (2022)

The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation
por: Liu, Bing, et al.
Publicado: (2019)

OGT Protein Interaction Network (OGT-PIN): A Curated Database of Experimentally Identified Interaction Proteins of OGT
por: Ma, Junfeng, et al.
Publicado: (2021)

A novel shark single-domain antibody targeting OGT as a tool for detection and intracellular localization
por: Xi, Xiaozhi, et al.
Publicado: (2023)

How Lipid-Specific T Cells Become Effectors: The Differentiation of iNKT Subsets
por: Wang, Haiguang, et al.
Publicado: (2018)

OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis
por: Li, Xiang, et al.
Publicado: (2023)

CCR7 defines a precursor for murine iNKT cells in thymus and periphery
por: Wang, Haiguang, et al.
Publicado: (2018)

OGT Ohio graduation test mathematics
por: Brice, J, et al.
Publicado: (2012)

OGT restrains the expansion of DNA damage signaling
por: Chen, Qiang, et al.
Publicado: (2016)

Every OGT Is Illuminated … by Fluorescent and Synchrotron Lights
por: Miggiano, Riccardo, et al.
Publicado: (2017)

Specificity of oligonucleotide gene therapy (OGT) agents
por: Nedorezova, Daria D., et al.
Publicado: (2022)

How the glycosyltransferase OGT catalyzes amide bond cleavage
por: Janetzko, John, et al.
Publicado: (2016)

OGT/HIF-2α axis promotes the progression of clear cell renal cell carcinoma and regulates its sensitivity to ferroptosis
por: Yang, Zhou, et al.
Publicado: (2023)

Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation
por: Li, Xinghui, et al.
Publicado: (2017)

Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation
por: Platanitis, Ekaterini, et al.
Publicado: (2018)

Adipocyte OGT governs diet-induced hyperphagia and obesity
por: Li, Min-Dian, et al.
Publicado: (2018)

Activation by NarL at the Escherichia coli ogt promoter
por: Ruanto, Patcharawarin, et al.
Publicado: (2020)

IL-10/STAT3/SOCS3 Axis Is Involved in the Anti-inflammatory Effect of Benznidazole
por: Cevey, Ágata C., et al.
Publicado: (2019)

Interleukin-2 and STAT5 in regulatory T cell development and function
por: Mahmud, Shawn A., et al.
Publicado: (2013)

From pre-DP, post-DP, SP4, and SP8 Thymocyte Cell Counts to a Dynamical Model of Cortical and Medullary Selection
por: Sawicka, Maria, et al.
Publicado: (2014)

MST1 controls murine neutrophil homeostasis via the G-CSFR/STAT3 axis
por: Masgrau-Alsina, Sergi, et al.
Publicado: (2022)

Post-transcriptional regulatory feedback encodes JAK-STAT signal memory of interferon stimulation
por: Kalliara, Eirini, et al.
Publicado: (2022)

Distinct OGT-Binding Sites Promote HCF-1 Cleavage
por: Bhuiyan, Tanja, et al.
Publicado: (2015)

Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors
por: Lim, Sungsu, et al.
Publicado: (2015)

STAT6 Pathway Is Critical for the Induction and Function of Regulatory T Cells Induced by Mucosal B Cells
por: Chu, Kuan-Hua, et al.
Publicado: (2021)

Brown adipose tissue involution associated with progressive restriction in progenitor competence
por: Huang, Zan, et al.
Publicado: (2022)

SIRT1 regulates O-GlcNAcylation of tau through OGT
por: Lu, Shu, et al.
Publicado: (2020)

Quantitative Proteomics Reveals that the OGT Interactome Is Remodeled in Response to Oxidative Stress
por: Martinez, Marissa, et al.
Publicado: (2021)

Ventromedial hypothalamic OGT drives adipose tissue lipolysis and curbs obesity
por: Wang, Qi, et al.
Publicado: (2022)

Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression
por: Tengesdal, Isak W., et al.
Publicado: (2021)

Type III interferon drives thymic B cell activation and regulatory T cell generation
por: Martinez, Ryan J., et al.
Publicado: (2023)

The nutrient sensor OGT regulates Hipk stability and tumorigenic-like activities in Drosophila
por: Wong, Kenneth Kin Lam, et al.
Publicado: (2020)

Double-Edged Sword: Interleukin-2 Promotes T Regulatory Cell Differentiation but Also Expands Interleukin-13- and Interferon-γ-Producing CD8(+) T Cells via STAT6-GATA-3 Axis in Systemic Lupus Erythematosus
por: Kato, Hiroshi, et al.
Publicado: (2021)

Monocyte-Derived Dendritic Cell Differentiation in Inflammatory Arthritis Is Regulated by the JAK/STAT Axis via NADPH Oxidase Regulation
por: Marzaioli, Viviana, et al.
Publicado: (2020)

The Non-Receptor Protein Tyrosine Phosphatase PTPN6 Mediates a Positive Regulatory Approach From the Interferon Regulatory Factor to the JAK/STAT Pathway in Litopenaeus vannamei
por: Luo, Mengting, et al.
Publicado: (2022)

Hsa-miR-31 Governs T-Cell Homeostasis in HIV Protection via IFN-γ-Stat1-T-Bet Axis
por: Zhu, Lingyan, et al.
Publicado: (2021)

Adiponectin/AdipoR1 Axis Promotes IL-10 Release by Human Regulatory T Cells
por: Ramos-Ramírez, Patricia, et al.
Publicado: (2021)

T(REG)king From Gut to Brain: The Control of Regulatory T Cells Along the Gut-Brain Axis
por: Choi, Juli, et al.
Publicado: (2022)

The potential regulatory role of the lncRNA-miRNA-mRNA axis in teleost fish
por: Zhou, Zhixia, et al.
Publicado: (2023)

Targeting STAT3 Abrogates Tim-3 Upregulation of Adaptive Resistance to PD-1 Blockade on Regulatory T Cells of Melanoma
por: Huang, Lili, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_iqvdps3r6a497eob2q6sqtu03k