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A Planar Culture Model of Human Absorptive Enterocytes Reveals Metformin Increases Fatty Acid Oxidation and Export

BACKGROUND & AIMS: Fatty acid oxidation by absorptive enterocytes has been linked to the pathophysiology of type 2 diabetes, obesity, and dyslipidemia. Caco-2 and organoids have been used to study dietary lipid-handling processes including fatty acid oxidation, but are limited in physiological r...

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Detalles Bibliográficos
Autores principales:	Gomez-Martinez, Ismael, Bliton, R. Jarrett, Breau, Keith A., Czerwinski, Michael J., Williamson, Ian A., Wen, Jia, Rawls, John F., Magness, Scott T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305019/ https://www.ncbi.nlm.nih.gov/pubmed/35489715 http://dx.doi.org/10.1016/j.jcmgh.2022.04.009

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