A randomized placebo‐controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis

INTRODUCTION/AIMS: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative illness with great unmet patient need. We aimed to evaluate whether mesenchymal stem cells induced to secrete high levels of neurotrophic factors (MSC‐NTF), a novel autologous cell‐therapy capable of targeting multip...

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Detalles Bibliográficos
Autores principales: Cudkowicz, Merit E., Lindborg, Stacy R., Goyal, Namita A., Miller, Robert G., Burford, Matthew J., Berry, James D., Nicholson, Katharine A., Mozaffar, Tahseen, Katz, Jonathan S., Jenkins, Liberty J., Baloh, Robert H., Lewis, Richard A., Staff, Nathan P., Owegi, Margaret A., Berry, Donald A., Gothelf, Yael, Levy, Yossef S., Aricha, Revital, Kern, Ralph Z., Windebank, Anthony J., Brown, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Clinical Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305113/
https://www.ncbi.nlm.nih.gov/pubmed/34890069
http://dx.doi.org/10.1002/mus.27472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305113/
https://www.ncbi.nlm.nih.gov/pubmed/34890069
http://dx.doi.org/10.1002/mus.27472

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