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Photoswitchable Epothilone‐Based Microtubule Stabilisers Allow GFP‐Imaging‐Compatible, Optical Control over the Microtubule Cytoskeleton

Optical methods to modulate microtubule dynamics show promise for reaching the micron‐ and millisecond‐scale resolution needed to decrypt the roles of the cytoskeleton in biology. However, optical microtubule stabilisers are under‐developed. We introduce “STEpos” as GFP‐orthogonal, light‐responsive...

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Detalles Bibliográficos
Autores principales: Gao, Li, Meiring, Joyce C. M., Heise, Constanze, Rai, Ankit, Müller‐Deku, Adrian, Akhmanova, Anna, Thorn‐Seshold, Julia, Thorn‐Seshold, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305116/
https://www.ncbi.nlm.nih.gov/pubmed/34902214
http://dx.doi.org/10.1002/anie.202114614