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Total Synthesis of Mycinamicin IV as Integral Part of a Collective Approach to Macrolide Antibiotics

The total synthesis of the 16‐membered macrolide mycinamicin IV is outlined, which complements our previously disclosed, largely catalysis‐based route to the aglycone. This work must also be seen in the context of our recent conquest of aldgamycin N, a related antibiotic featuring a similar core but...

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Detalles Bibliográficos
Autores principales: Späth, Georg, Fürstner, Alois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305142/
https://www.ncbi.nlm.nih.gov/pubmed/34910333
http://dx.doi.org/10.1002/chem.202104400