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Mitochondrial-Dependent and Independent Functions of PINK1

PINK1 has been characterized as a mitochondrial kinase that can target to damaged mitochondria to initiate mitophagy, a process to remove unhealthy mitochondria for protecting neuronal cells. Mutations of the human PINK1 gene are also found to cause early onset Parkinson’s disease, a neurodegenerati...

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Detalles Bibliográficos
Autores principales: Chen, Xiusheng, Wang, Qi, Li, Shihua, Li, Xiao-Jiang, Yang, Weili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305176/
https://www.ncbi.nlm.nih.gov/pubmed/35874823
http://dx.doi.org/10.3389/fcell.2022.954536

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