Exploring the enzyme‐catalyzed synthesis of isotope labeled cyclopropanes

Cyclopropanes are commonly employed structural moieties in drug design since their incorporation is often associated with increased target affinity, improved metabolic stability, and increased rigidity to access bioactive conformations. Robust chemical cyclopropanation procedures have been developed...

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Detalles Bibliográficos
Autores principales: Sardana, Malvika, Mühlfenzl, Kim S., Wenker, Sylvia T. M., Åkesson, Christian, Hayes, Martin A., Elmore, Charles S., Pithani, Subhash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305206/
https://www.ncbi.nlm.nih.gov/pubmed/34997781
http://dx.doi.org/10.1002/jlcr.3962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305206/
https://www.ncbi.nlm.nih.gov/pubmed/34997781
http://dx.doi.org/10.1002/jlcr.3962

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