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Phosphatidic acid phosphatase 1 impairs SARS-CoV-2 replication by affecting the glycerophospholipid metabolism pathway

Viruses exploit the host lipid metabolism machinery to achieve efficient replication. We herein characterize the lipids profile reprogramming in vitro and in vivo using liquid chromatography-mass spectrometry-based untargeted lipidomics. The lipidome of SARS-CoV-2-infected Caco-2 cells was markedly...

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Detalles Bibliográficos
Autores principales:	Yan, Bingpeng, Yuan, Shuofeng, Cao, Jianli, Fung, Kingchun, Lai, Pok-Man, Yin, Feifei, Sze, Kong-Hung, Qin, Zhenzhi, Xie, Yubin, Ye, Zi-Wei, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Tsang, Jessica Oi-Ling, Zou, Zijiao, Chan, Chris Chun-Yiu, Luo, Cuiting, Cai, Jian-Piao, Chan, Kwok-Hung, Chung, Tom Wai-Hing, Tam, Anthony Raymond, Chu, Hin, Jin, Dong-Yan, Hung, Ivan Fan-Ngai, Yuen, Kwok-Yung, Kao, Richard Yi-Tsun, Chan, Jasper Fuk-Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305268/ https://www.ncbi.nlm.nih.gov/pubmed/35874954 http://dx.doi.org/10.7150/ijbs.73057

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