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Model to predict on‐treatment restoration of functional HBV‐specific CD8 (+) cell response foresees off‐treatment HBV control in eAg‐negative chronic hepatitis B

BACKGROUND: Hepatitis B virus (HBV)‐specific CD8(+) cell response restoration during nucleos(t)ide analogue (NUC) treatment could lead to off‐treatment HBV control in e‐antigen‐negative chronic hepatitis B (CHBe(−)). AIM: To predict this response with variables involved in T‐cell exhaustion for use...

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Detalles Bibliográficos
Autores principales: Peña‐Asensio, Julia, Calvo, Henar, Miquel, Joaquín, Sanz‐de‐Villalobos, Eduardo, González‐Praetorius, Alejandro, Torralba, Miguel, Larrubia, Juan‐Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305412/
https://www.ncbi.nlm.nih.gov/pubmed/35224746
http://dx.doi.org/10.1111/apt.16850