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Metabolic analysis of the asparagine and glutamine dynamics in an industrial Chinese hamster ovary fed‐batch process

Chinese hamster ovary (CHO) cell lines are grown in cultures with varying asparagine and glutamine concentrations, but further study is needed to characterize the interplay between these amino acids. By following (13)C‐glucose, (13)C‐glutamine, and (13)C‐asparagine tracers using metabolic flux analy...

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Detalles Bibliográficos
Autores principales:	Kirsch, Brian J., Bennun, Sandra V., Mendez, Adam, Johnson, Amy S., Wang, Hongxia, Qiu, Haibo, Li, Ning, Lawrence, Shawn M., Bak, Hanne, Betenbaugh, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305493/ https://www.ncbi.nlm.nih.gov/pubmed/34786689 http://dx.doi.org/10.1002/bit.27993

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