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Association of the COVID‐19 outbreak with acute stroke care in Switzerland

BACKGROUND AND PURPOSE: In Switzerland, the COVID‐19 incidence during the first pandemic wave was high. Our aim was to assess the association of the outbreak with acute stroke care in Switzerland in spring 2020. METHODS: This was a retrospective analysis based on the Swiss Stroke Registry, which inc...

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Autores principales: De Marchis, Gian Marco, Wright, Patrick R., Michel, Patrik, Strambo, Davide, Carrera, Emmanuel, Dirren, Elisabeth, Luft, Andreas R., Wegener, Susanne, Cereda, Carlo W., Kägi, Georg, Vehoff, Jochen, Gensicke, Henrik, Lyrer, Philippe, Nedeltchev, Krassen, Khales, Timo, Bolognese, Manuel, Salmen, Stephan, Sturzenegger, Rolf, Bonvin, Christophe, Berger, Christian, Schelosky, Ludwig, Mono, Marie‐Luise, Rodic, Biljana, von Reding, Andrea, Schwegler, Guido, Tarnutzer, Alexander A., Medlin, Friedrich, Humm, Andrea M., Peters, Nils, Beyeler, Morin, Kriemler, Lilian, Bervini, David, Fandino, Javier, Hemkens, Lars G., Mordasini, Pasquale, Arnold, Marcel, Fischer, Urs, Bonati, Leo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305499/
https://www.ncbi.nlm.nih.gov/pubmed/34894018
http://dx.doi.org/10.1111/ene.15209
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author De Marchis, Gian Marco
Wright, Patrick R.
Michel, Patrik
Strambo, Davide
Carrera, Emmanuel
Dirren, Elisabeth
Luft, Andreas R.
Wegener, Susanne
Cereda, Carlo W.
Kägi, Georg
Vehoff, Jochen
Gensicke, Henrik
Lyrer, Philippe
Nedeltchev, Krassen
Khales, Timo
Bolognese, Manuel
Salmen, Stephan
Sturzenegger, Rolf
Bonvin, Christophe
Berger, Christian
Schelosky, Ludwig
Mono, Marie‐Luise
Rodic, Biljana
von Reding, Andrea
Schwegler, Guido
Tarnutzer, Alexander A.
Medlin, Friedrich
Humm, Andrea M.
Peters, Nils
Beyeler, Morin
Kriemler, Lilian
Bervini, David
Fandino, Javier
Hemkens, Lars G.
Mordasini, Pasquale
Arnold, Marcel
Fischer, Urs
Bonati, Leo H.
author_facet De Marchis, Gian Marco
Wright, Patrick R.
Michel, Patrik
Strambo, Davide
Carrera, Emmanuel
Dirren, Elisabeth
Luft, Andreas R.
Wegener, Susanne
Cereda, Carlo W.
Kägi, Georg
Vehoff, Jochen
Gensicke, Henrik
Lyrer, Philippe
Nedeltchev, Krassen
Khales, Timo
Bolognese, Manuel
Salmen, Stephan
Sturzenegger, Rolf
Bonvin, Christophe
Berger, Christian
Schelosky, Ludwig
Mono, Marie‐Luise
Rodic, Biljana
von Reding, Andrea
Schwegler, Guido
Tarnutzer, Alexander A.
Medlin, Friedrich
Humm, Andrea M.
Peters, Nils
Beyeler, Morin
Kriemler, Lilian
Bervini, David
Fandino, Javier
Hemkens, Lars G.
Mordasini, Pasquale
Arnold, Marcel
Fischer, Urs
Bonati, Leo H.
author_sort De Marchis, Gian Marco
collection PubMed
description BACKGROUND AND PURPOSE: In Switzerland, the COVID‐19 incidence during the first pandemic wave was high. Our aim was to assess the association of the outbreak with acute stroke care in Switzerland in spring 2020. METHODS: This was a retrospective analysis based on the Swiss Stroke Registry, which includes consecutive patients with acute cerebrovascular events admitted to Swiss Stroke Units and Stroke Centers. A linear model was fitted to the weekly admission from 2018 and 2019 and was used to quantify deviations from the expected weekly admissions from 13 March to 26 April 2020 (the “lockdown period”). Characteristics and 3‐month outcome of patients admitted during the lockdown period were compared with patients admitted during the same calendar period of 2018 and 2019. RESULTS: In all, 28,310 patients admitted between 1 January 2018 and 26 April 2020 were included. Of these, 4491 (15.9%) were admitted in the periods March 13–April 26 of the years 2018–2020. During the lockdown in 2020, the weekly admissions dropped by up to 22% compared to rates expected from 2018 and 2019. During three consecutive weeks, weekly admissions fell below the 5% quantile (likelihood 0.38%). The proportion of intracerebral hemorrhage amongst all registered admissions increased from 7.1% to 9.3% (p = 0.006), and numerically less severe strokes were observed (median National Institutes of Health Stroke Scale from 3 to 2, p = 0.07). CONCLUSIONS: Admissions and clinical severity of acute cerebrovascular events decreased substantially during the lockdown in Switzerland. Delivery and quality of acute stroke care were maintained.
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spelling pubmed-93054992022-07-28 Association of the COVID‐19 outbreak with acute stroke care in Switzerland De Marchis, Gian Marco Wright, Patrick R. Michel, Patrik Strambo, Davide Carrera, Emmanuel Dirren, Elisabeth Luft, Andreas R. Wegener, Susanne Cereda, Carlo W. Kägi, Georg Vehoff, Jochen Gensicke, Henrik Lyrer, Philippe Nedeltchev, Krassen Khales, Timo Bolognese, Manuel Salmen, Stephan Sturzenegger, Rolf Bonvin, Christophe Berger, Christian Schelosky, Ludwig Mono, Marie‐Luise Rodic, Biljana von Reding, Andrea Schwegler, Guido Tarnutzer, Alexander A. Medlin, Friedrich Humm, Andrea M. Peters, Nils Beyeler, Morin Kriemler, Lilian Bervini, David Fandino, Javier Hemkens, Lars G. Mordasini, Pasquale Arnold, Marcel Fischer, Urs Bonati, Leo H. Eur J Neurol Stroke BACKGROUND AND PURPOSE: In Switzerland, the COVID‐19 incidence during the first pandemic wave was high. Our aim was to assess the association of the outbreak with acute stroke care in Switzerland in spring 2020. METHODS: This was a retrospective analysis based on the Swiss Stroke Registry, which includes consecutive patients with acute cerebrovascular events admitted to Swiss Stroke Units and Stroke Centers. A linear model was fitted to the weekly admission from 2018 and 2019 and was used to quantify deviations from the expected weekly admissions from 13 March to 26 April 2020 (the “lockdown period”). Characteristics and 3‐month outcome of patients admitted during the lockdown period were compared with patients admitted during the same calendar period of 2018 and 2019. RESULTS: In all, 28,310 patients admitted between 1 January 2018 and 26 April 2020 were included. Of these, 4491 (15.9%) were admitted in the periods March 13–April 26 of the years 2018–2020. During the lockdown in 2020, the weekly admissions dropped by up to 22% compared to rates expected from 2018 and 2019. During three consecutive weeks, weekly admissions fell below the 5% quantile (likelihood 0.38%). The proportion of intracerebral hemorrhage amongst all registered admissions increased from 7.1% to 9.3% (p = 0.006), and numerically less severe strokes were observed (median National Institutes of Health Stroke Scale from 3 to 2, p = 0.07). CONCLUSIONS: Admissions and clinical severity of acute cerebrovascular events decreased substantially during the lockdown in Switzerland. Delivery and quality of acute stroke care were maintained. John Wiley and Sons Inc. 2022-01-04 2022-03 /pmc/articles/PMC9305499/ /pubmed/34894018 http://dx.doi.org/10.1111/ene.15209 Text en © 2021 The Authors. European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Stroke
De Marchis, Gian Marco
Wright, Patrick R.
Michel, Patrik
Strambo, Davide
Carrera, Emmanuel
Dirren, Elisabeth
Luft, Andreas R.
Wegener, Susanne
Cereda, Carlo W.
Kägi, Georg
Vehoff, Jochen
Gensicke, Henrik
Lyrer, Philippe
Nedeltchev, Krassen
Khales, Timo
Bolognese, Manuel
Salmen, Stephan
Sturzenegger, Rolf
Bonvin, Christophe
Berger, Christian
Schelosky, Ludwig
Mono, Marie‐Luise
Rodic, Biljana
von Reding, Andrea
Schwegler, Guido
Tarnutzer, Alexander A.
Medlin, Friedrich
Humm, Andrea M.
Peters, Nils
Beyeler, Morin
Kriemler, Lilian
Bervini, David
Fandino, Javier
Hemkens, Lars G.
Mordasini, Pasquale
Arnold, Marcel
Fischer, Urs
Bonati, Leo H.
Association of the COVID‐19 outbreak with acute stroke care in Switzerland
title Association of the COVID‐19 outbreak with acute stroke care in Switzerland
title_full Association of the COVID‐19 outbreak with acute stroke care in Switzerland
title_fullStr Association of the COVID‐19 outbreak with acute stroke care in Switzerland
title_full_unstemmed Association of the COVID‐19 outbreak with acute stroke care in Switzerland
title_short Association of the COVID‐19 outbreak with acute stroke care in Switzerland
title_sort association of the covid‐19 outbreak with acute stroke care in switzerland
topic Stroke
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305499/
https://www.ncbi.nlm.nih.gov/pubmed/34894018
http://dx.doi.org/10.1111/ene.15209
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