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Somatic DNA Damage Response and Homologous Repair Gene Alterations and Its Association With Tumor Variant Burden in Breast Cancer Patients With Occupational Exposure to Pesticides
Homologous recombination is a crucial pathway that is specialized in repairing double-strand breaks; thus, alterations in genes of this pathway may lead to loss of genomic stability and cell growth suppression. Pesticide exposure potentially increases cancer risk through several mechanisms, such as...
Autores principales: | Scandolara, Thalita Basso, Valle, Sara Ferreira, Esteves, Cristiane, Scherer, Nicole de Miranda, de Armas, Elvismary Molina, Furtado, Carolina, Gomes, Renan, Boroni, Mariana, Jaques, Hellen dos Santos, Alves, Fernanda Mara, Rech, Daniel, Panis, Carolina, Bonvicino, Cibele Rodrigues |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305859/ https://www.ncbi.nlm.nih.gov/pubmed/35875117 http://dx.doi.org/10.3389/fonc.2022.904813 |
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