Cargando…

LRRK2‐G2019S mice display alterations in glutamatergic synaptic transmission in midbrain dopamine neurons

The progressive degeneration of dopamine (DA) neurons in the substantia nigra compacta (SNc) leads to the emergence of motor symptoms in patients with Parkinson's disease (PD). To propose neuroprotective therapies able to slow or halt the progression of the disease, it is necessary to identify...

Descripción completa

Detalles Bibliográficos
Autores principales:	Skiteva, Olga, Yao, Ning, Sitzia, Giacomo, Chergui, Karima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305867/ https://www.ncbi.nlm.nih.gov/pubmed/35152441 http://dx.doi.org/10.1111/jnc.15588

Ejemplares similares

Neuronal Firing and Glutamatergic Synapses in the Substantia Nigra Pars Reticulata of LRRK2-G2019S Mice
por: Sitzia, Giacomo, et al.
Publicado: (2022)

Age- and Sex-Dependent Behavioral and Neurochemical Alterations in hLRRK2-G2019S BAC Mice
por: Yao, Ning, et al.
Publicado: (2022)

Aberrant somatic calcium channel function in cNurr1 and LRRK2-G2019S mice
por: Skiteva, Olga, et al.
Publicado: (2023)

Ketamine induces opposite changes in AMPA receptor calcium permeability in the ventral tegmental area and nucleus accumbens
por: Skiteva, Olga, et al.
Publicado: (2021)

Reliability in the Identification of Midbrain Dopamine Neurons
por: Margolis, Elyssa B., et al.
Publicado: (2010)

Caffeine Controls Glutamatergic Synaptic Transmission and Pyramidal Neuron Excitability in Human Neocortex
por: Kerkhofs, Amber, et al.
Publicado: (2018)

Inhibitory co-transmission from midbrain dopamine neurons relies on presynaptic GABA uptake
por: Melani, Riccardo, et al.
Publicado: (2022)

Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice
por: Beccano-Kelly, Dayne A., et al.
Publicado: (2014)

Salsolinol Facilitates Glutamatergic Transmission to Dopamine Neurons in the Posterior Ventral Tegmental Area of Rats
por: Xie, Guiqin, et al.
Publicado: (2012)

Direct Glutamatergic Signaling From Midbrain Dopaminergic Neurons Onto Pyramidal Prefrontal Cortex Neurons
por: Pérez-López, José Luis, et al.
Publicado: (2018)

Purity and Enrichment of Laser-Microdissected Midbrain Dopamine Neurons
por: Brown, Amanda L., et al.
Publicado: (2013)

Midbrain dopamine neurons arbiter OCD-like behavior
por: Xue, Jinwen, et al.
Publicado: (2022)

Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids
por: Kim, Hongwon, et al.
Publicado: (2019)

Interleukin-10 Facilitates Glutamatergic Synaptic Transmission and Homeostatic Plasticity in Cultured Hippocampal Neurons
por: Nenov, Miroslav N., et al.
Publicado: (2019)

Morphine disinhibits glutamatergic input to VTA dopamine neurons and promotes dopamine neuron excitation
por: Chen, Ming, et al.
Publicado: (2015)

Commentary on “Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice”
por: Popugaeva, Elena, et al.
Publicado: (2014)

Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis
por: Tritsch, Nicolas X, et al.
Publicado: (2014)

Ketamine disrupts neuromodulatory control of glutamatergic synaptic transmission
por: Lur, Gyorgy, et al.
Publicado: (2019)

Glutamate neurons are intermixed with midbrain dopamine neurons in nonhuman primates and humans
por: Root, David H., et al.
Publicado: (2016)

Sumatriptan inhibits synaptic transmission in the rat midbrain periaqueductal grey
por: Jeong, Hyo-Jin, et al.
Publicado: (2008)

Endocannabinoid Signaling in Midbrain Dopamine Neurons: More than Physiology?
por: Melis, M, et al.
Publicado: (2007)

Human‐Specific Transcriptome of Ventral and Dorsal Midbrain Dopamine Neurons
por: Monzón‐Sandoval, Jimena, et al.
Publicado: (2020)

Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia
por: Purves-Tyson, Tertia D., et al.
Publicado: (2021)

Midbrain Gene Screening Identifies a New Mesoaccumbal Glutamatergic Pathway and a Marker for Dopamine Cells Neuroprotected in Parkinson’s Disease
por: Viereckel, Thomas, et al.
Publicado: (2016)

Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats
por: Cardoso, Tiago, et al.
Publicado: (2018)

Potentiation of Glutamatergic Synaptic Transmission Onto Dorsal Raphe Serotonergic Neurons in the Valproic Acid Model of Autism
por: Wang, Ruixiang, et al.
Publicado: (2018)

The Role of Mesostriatal Dopamine System and Corticostriatal Glutamatergic Transmission in Chronic Pain
por: Ziółkowska, Barbara
Publicado: (2021)

Epac2 in midbrain dopamine neurons contributes to cocaine reinforcement via enhancement of dopamine release
por: Liu, Xiaojie, et al.
Publicado: (2022)

Rapid regulation of depression-related behaviors by control of midbrain dopamine neurons
por: Chaudhury, Dipesh, et al.
Publicado: (2012)

Visualization of plasticity in fear-evoked calcium signals in midbrain dopamine neurons
por: Gore, Bryan B., et al.
Publicado: (2014)

Phasic Stimulation of Midbrain Dopamine Neuron Activity Reduces Salt Consumption
por: Sandhu, Eleanor C., et al.
Publicado: (2018)

An Optimized Protocol for the Generation of Midbrain Dopamine Neurons under Defined Conditions
por: Gantner, Carlos W., et al.
Publicado: (2020)

Subcellular and regional localization of mRNA translation in midbrain dopamine neurons
por: Hobson, Benjamin D., et al.
Publicado: (2022)

Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction
por: Luján, Miguel Á., et al.
Publicado: (2023)

Revealing the contribution of astrocytes to glutamatergic neuronal transmission
por: Cuellar-Santoyo, Ares Orlando, et al.
Publicado: (2023)

Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA
por: Wei, Chao, et al.
Publicado: (2018)

The Effect of Bacterial Endotoxin LPS on Serotonergic Modulation of Glutamatergic Synaptic Transmission
por: Bernard, Jate, et al.
Publicado: (2020)

Dysfunction of Glutamatergic Synaptic Transmission in Depression: Focus on AMPA Receptor Trafficking
por: He, Jin-Gang, et al.
Publicado: (2022)

Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference
por: Trubetckaia, Olga, et al.
Publicado: (2019)

Hemodynamic Responses Evoked by Neuronal Stimulation via Channelrhodopsin-2 Can Be Independent of Intracortical Glutamatergic Synaptic Transmission
por: Scott, Nadia A., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pg7t378esf8ait7m3gesic5mt3