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Titanocene(III)‐Catalyzed Precision Deuteration of Epoxides

We describe a titanocene(III)‐catalyzed deuterosilylation of epoxides that provides β‐deuterated anti‐Markovnikov alcohols with excellent D‐incorporation, in high yield, and often excellent diastereoselectivity after desilylation. The key to the success of the reaction is a novel activation method o...

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Detalles Bibliográficos
Autores principales:	Henriques, Dina Schwarz G., Rojo‐Wiechel, Elena, Klare, Sven, Mika, Regine, Höthker, Sebastian, Schacht, Jonathan H., Schmickler, Niklas, Gansäuer, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305931/ https://www.ncbi.nlm.nih.gov/pubmed/34845824 http://dx.doi.org/10.1002/anie.202114198

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