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A quantitative FLASH effectiveness model to reveal potentials and pitfalls of high dose rate proton therapy

PURPOSE: In ultrahigh dose rate radiotherapy, the FLASH effect can lead to substantially reduced healthy tissue damage without affecting tumor control. Although many studies show promising results, the underlying biological mechanisms and the relevant delivery parameters are still largely unknown. I...

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Detalles Bibliográficos
Autores principales: Krieger, Miriam, van de Water, Steven, Folkerts, Michael M., Mazal, Alejandro, Fabiano, Silvia, Bizzocchi, Nicola, Weber, Damien C., Safai, Sairos, Lomax, Antony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305944/
https://www.ncbi.nlm.nih.gov/pubmed/35032035
http://dx.doi.org/10.1002/mp.15459