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hUC-EVs-ATO reduce the severity of acute GVHD by resetting inflammatory macrophages toward the M2 phenotype

BACKGROUND: Both extracellular vesicles from mesenchymal stromal cell-derived human umbilical cords (hUC-EVs) and arsenic trioxides (ATOs) have been demonstrated to treat acute graft-versus-host disease (aGVHD) via immunomodulation. Apart from immunomodulation, hUC-EVs have a unique function of drug...

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Detalles Bibliográficos
Autores principales:	Su, Yan, Sun, Xueyan, Liu, Xiao, Qu, Qingyuan, Yang, Liping, Chen, Qi, Liu, Fengqi, Li, Yueying, Wang, Qianfei, Huang, Bo, Huang, Xiao-Hui, Zhang, Xiao-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306027/ https://www.ncbi.nlm.nih.gov/pubmed/35864538 http://dx.doi.org/10.1186/s13045-022-01315-2

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