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Mitochondria dysfunction in CD8+ T cells as an important contributing factor for cancer development and a potential target for cancer treatment: a review

CD8+ T cells play a central role in anti-tumor immunity. Naïve CD8+ T cells are active upon tumor antigen stimulation, and then differentiate into functional cells and migrate towards the tumor sites. Activated CD8+ T cells can directly destroy tumor cells by releasing perforin and granzymes and ind...

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Detalles Bibliográficos
Autores principales:	Zhang, Lu, Zhang, Wen, Li, Ziye, Lin, Shumeng, Zheng, Tiansheng, Hao, Bingjie, Hou, Yaqin, Zhang, Yanfei, Wang, Kai, Qin, Chenge, Yue, Liduo, Jin, Jing, Li, Ming, Fan, Lihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306053/ https://www.ncbi.nlm.nih.gov/pubmed/35864520 http://dx.doi.org/10.1186/s13046-022-02439-6

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