Transplanted allogeneic cardiac progenitor cells secrete GDF-15 and stimulate an active immune remodeling process in the ischemic myocardium

BACKGROUND: Despite promising results in clinical studies, the mechanism for the beneficial effects of allogenic cell-based therapies remains unclear. Macrophages are not only critical mediators of inflammation but also critical players in cardiac remodeling. We hypothesized that transplanted alloge...

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Detalles Bibliográficos
Autores principales: Mishra, Rachana, Saha, Progyaparamita, Datla, Srinivasa Raju, Mellacheruvu, Pranav, Gunasekaran, Muthukumar, Guru, Sameer Ahmad, Fu, Xubin, Chen, Ling, Bolli, Roberto, Sharma, Sudhish, Kaushal, Sunjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306063/
https://www.ncbi.nlm.nih.gov/pubmed/35864544
http://dx.doi.org/10.1186/s12967-022-03534-0

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