Cargando…

Discontinuing methotrexate to enhance vaccine response

In patients with autoimmune rheumatic disease, methotrexate therapy has been associated with poor immune response to vaccines, including those intended to provide protection against COVID-19. Emerging evidence supports the practice of temporarily discontinuing this treatment in order to improve immu...

Descripción completa

Detalles Bibliográficos
Autores principales: Medeiros-Ribeiro, Ana C., Aikawa, Nadia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306233/
https://www.ncbi.nlm.nih.gov/pubmed/35869395
http://dx.doi.org/10.1038/s41584-022-00817-0
Descripción
Sumario:In patients with autoimmune rheumatic disease, methotrexate therapy has been associated with poor immune response to vaccines, including those intended to provide protection against COVID-19. Emerging evidence supports the practice of temporarily discontinuing this treatment in order to improve immunogenicity.