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Discontinuing methotrexate to enhance vaccine response
In patients with autoimmune rheumatic disease, methotrexate therapy has been associated with poor immune response to vaccines, including those intended to provide protection against COVID-19. Emerging evidence supports the practice of temporarily discontinuing this treatment in order to improve immu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306233/ https://www.ncbi.nlm.nih.gov/pubmed/35869395 http://dx.doi.org/10.1038/s41584-022-00817-0 |
| _version_ | 1784752500958560256 |
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| author | Medeiros-Ribeiro, Ana C. Aikawa, Nadia E. |
| author_facet | Medeiros-Ribeiro, Ana C. Aikawa, Nadia E. |
| author_sort | Medeiros-Ribeiro, Ana C. |
| collection | PubMed |
| description | In patients with autoimmune rheumatic disease, methotrexate therapy has been associated with poor immune response to vaccines, including those intended to provide protection against COVID-19. Emerging evidence supports the practice of temporarily discontinuing this treatment in order to improve immunogenicity. |
| format | Online Article Text |
| id | pubmed-9306233 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-93062332022-07-25 Discontinuing methotrexate to enhance vaccine response Medeiros-Ribeiro, Ana C. Aikawa, Nadia E. Nat Rev Rheumatol News & Views In patients with autoimmune rheumatic disease, methotrexate therapy has been associated with poor immune response to vaccines, including those intended to provide protection against COVID-19. Emerging evidence supports the practice of temporarily discontinuing this treatment in order to improve immunogenicity. Nature Publishing Group UK 2022-07-22 2022 /pmc/articles/PMC9306233/ /pubmed/35869395 http://dx.doi.org/10.1038/s41584-022-00817-0 Text en © Springer Nature Limited 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| spellingShingle | News & Views Medeiros-Ribeiro, Ana C. Aikawa, Nadia E. Discontinuing methotrexate to enhance vaccine response |
| title | Discontinuing methotrexate to enhance vaccine response |
| title_full | Discontinuing methotrexate to enhance vaccine response |
| title_fullStr | Discontinuing methotrexate to enhance vaccine response |
| title_full_unstemmed | Discontinuing methotrexate to enhance vaccine response |
| title_short | Discontinuing methotrexate to enhance vaccine response |
| title_sort | discontinuing methotrexate to enhance vaccine response |
| topic | News & Views |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306233/ https://www.ncbi.nlm.nih.gov/pubmed/35869395 http://dx.doi.org/10.1038/s41584-022-00817-0 |
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