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Prediction of COVID-19 diagnosis based on openEHR artefacts

Nowadays, we are facing the worldwide pandemic caused by COVID-19. The complexity and momentum of monitoring patients infected with this virus calls for the usage of agile and scalable data structure methodologies. OpenEHR is a healthcare standard that is attracting a lot of attention in recent year...

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Autores principales: Oliveira, Daniela, Ferreira, Diana, Abreu, Nuno, Leuschner, Pedro, Abelha, António, Machado, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306245/
https://www.ncbi.nlm.nih.gov/pubmed/35869091
http://dx.doi.org/10.1038/s41598-022-15968-z
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author Oliveira, Daniela
Ferreira, Diana
Abreu, Nuno
Leuschner, Pedro
Abelha, António
Machado, José
author_facet Oliveira, Daniela
Ferreira, Diana
Abreu, Nuno
Leuschner, Pedro
Abelha, António
Machado, José
author_sort Oliveira, Daniela
collection PubMed
description Nowadays, we are facing the worldwide pandemic caused by COVID-19. The complexity and momentum of monitoring patients infected with this virus calls for the usage of agile and scalable data structure methodologies. OpenEHR is a healthcare standard that is attracting a lot of attention in recent years due to its comprehensive and robust architecture. The importance of an open, standardized and adaptable approach to clinical data lies in extracting value to generate useful knowledge that really can help healthcare professionals make an assertive decision. This importance is even more accentuated when facing a pandemic context. Thus, in this study, a system for tracking symptoms and health conditions of suspected or confirmed SARS-CoV-2 patients from a Portuguese hospital was developed using openEHR. All data on the evolutionary status of patients in home care as well as the results of their COVID-19 test were used to train different ML algorithms, with the aim of developing a predictive model capable of identifying COVID-19 infections according to the severity of symptoms identified by patients. The CRISP-DM methodology was used to conduct this research. The results obtained were promising, with the best model achieving an accuracy of 96.25%, a precision of 99.91%, a sensitivity of 92.58%, a specificity of 99.92%, and an AUC of 0.963, using the Decision Tree algorithm and the Split Validation method. Hence, in the future, after further testing, the predictive model could be implemented in clinical decision support systems.
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spelling pubmed-93062452022-07-24 Prediction of COVID-19 diagnosis based on openEHR artefacts Oliveira, Daniela Ferreira, Diana Abreu, Nuno Leuschner, Pedro Abelha, António Machado, José Sci Rep Article Nowadays, we are facing the worldwide pandemic caused by COVID-19. The complexity and momentum of monitoring patients infected with this virus calls for the usage of agile and scalable data structure methodologies. OpenEHR is a healthcare standard that is attracting a lot of attention in recent years due to its comprehensive and robust architecture. The importance of an open, standardized and adaptable approach to clinical data lies in extracting value to generate useful knowledge that really can help healthcare professionals make an assertive decision. This importance is even more accentuated when facing a pandemic context. Thus, in this study, a system for tracking symptoms and health conditions of suspected or confirmed SARS-CoV-2 patients from a Portuguese hospital was developed using openEHR. All data on the evolutionary status of patients in home care as well as the results of their COVID-19 test were used to train different ML algorithms, with the aim of developing a predictive model capable of identifying COVID-19 infections according to the severity of symptoms identified by patients. The CRISP-DM methodology was used to conduct this research. The results obtained were promising, with the best model achieving an accuracy of 96.25%, a precision of 99.91%, a sensitivity of 92.58%, a specificity of 99.92%, and an AUC of 0.963, using the Decision Tree algorithm and the Split Validation method. Hence, in the future, after further testing, the predictive model could be implemented in clinical decision support systems. Nature Publishing Group UK 2022-07-22 /pmc/articles/PMC9306245/ /pubmed/35869091 http://dx.doi.org/10.1038/s41598-022-15968-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Oliveira, Daniela
Ferreira, Diana
Abreu, Nuno
Leuschner, Pedro
Abelha, António
Machado, José
Prediction of COVID-19 diagnosis based on openEHR artefacts
title Prediction of COVID-19 diagnosis based on openEHR artefacts
title_full Prediction of COVID-19 diagnosis based on openEHR artefacts
title_fullStr Prediction of COVID-19 diagnosis based on openEHR artefacts
title_full_unstemmed Prediction of COVID-19 diagnosis based on openEHR artefacts
title_short Prediction of COVID-19 diagnosis based on openEHR artefacts
title_sort prediction of covid-19 diagnosis based on openehr artefacts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306245/
https://www.ncbi.nlm.nih.gov/pubmed/35869091
http://dx.doi.org/10.1038/s41598-022-15968-z
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