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Myelofibrosis: Genetic Characteristics and the Emerging Therapeutic Landscape

Primary myelofibrosis (PMF) is one of three myeloproliferative neoplasms (MPN) that are morphologically and molecularly inter-related, the other two being polycythemia vera (PV) and essential thrombocythemia (ET). MPNs are characterized by JAK-STAT–activating JAK2, CALR, or MPL mutations that give r...

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Detalles Bibliográficos
Autores principales:	Tefferi, Ayalew, Gangat, Naseema, Pardanani, Animesh, Crispino, John D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306313/ https://www.ncbi.nlm.nih.gov/pubmed/34911786 http://dx.doi.org/10.1158/0008-5472.CAN-21-2930

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