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Relevance of pRB Loss in Human Malignancies

The retinoblastoma tumor suppressor protein (pRB) is a known regulator of cell-cycle control; however, recent studies identified critical functions for pRB in regulating cancer-associated gene networks that influence the DNA damage response, apoptosis, and cell metabolism. Understanding the impact o...

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Detalles Bibliográficos
Autores principales:	Mandigo, Amy C., Tomlins, Scott A., Kelly, William K., Knudsen, Karen E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306333/ https://www.ncbi.nlm.nih.gov/pubmed/34407969 http://dx.doi.org/10.1158/1078-0432.CCR-21-1565

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