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Guillain-Barré-Like Syndrome From Esophageal Squamous Cell Carcinoma
Guillain-Barré-like syndrome (GBS) has been noted in solid tumors such as hepatocellular carcinoma, gastric, breast, and colon cancer and is characterized by an ascending weakness generally with mild paresthesias; however, it has not been noted in esophageal squamous cell carcinoma. A 64-year-old wo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306455/ https://www.ncbi.nlm.nih.gov/pubmed/35891856 http://dx.doi.org/10.7759/cureus.26158 |
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author | Jordan, Aryanna Makarova, Alena Adashek, Jacob J |
author_facet | Jordan, Aryanna Makarova, Alena Adashek, Jacob J |
author_sort | Jordan, Aryanna |
collection | PubMed |
description | Guillain-Barré-like syndrome (GBS) has been noted in solid tumors such as hepatocellular carcinoma, gastric, breast, and colon cancer and is characterized by an ascending weakness generally with mild paresthesias; however, it has not been noted in esophageal squamous cell carcinoma. A 64-year-old woman with moderately differentiated squamous cell carcinoma of the upper esophagus receiving 5-fluorouracil and cisplatin chemotherapy concurrently with radiation therapy presented for two weeks of progressive lower extremity weakness and numbness. She experienced acute worsening of symptoms after her cisplatin infusion. She underwent a lumbar puncture that revealed findings consistent with GBS and she began treatment with intravenous immunoglobin. She had gradual improvement in her weakness and paresthesias and was discharged to an inpatient rehabilitation facility. This case documents the first noted association between GBS and esophageal squamous cell carcinoma. |
format | Online Article Text |
id | pubmed-9306455 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-93064552022-07-25 Guillain-Barré-Like Syndrome From Esophageal Squamous Cell Carcinoma Jordan, Aryanna Makarova, Alena Adashek, Jacob J Cureus Internal Medicine Guillain-Barré-like syndrome (GBS) has been noted in solid tumors such as hepatocellular carcinoma, gastric, breast, and colon cancer and is characterized by an ascending weakness generally with mild paresthesias; however, it has not been noted in esophageal squamous cell carcinoma. A 64-year-old woman with moderately differentiated squamous cell carcinoma of the upper esophagus receiving 5-fluorouracil and cisplatin chemotherapy concurrently with radiation therapy presented for two weeks of progressive lower extremity weakness and numbness. She experienced acute worsening of symptoms after her cisplatin infusion. She underwent a lumbar puncture that revealed findings consistent with GBS and she began treatment with intravenous immunoglobin. She had gradual improvement in her weakness and paresthesias and was discharged to an inpatient rehabilitation facility. This case documents the first noted association between GBS and esophageal squamous cell carcinoma. Cureus 2022-06-21 /pmc/articles/PMC9306455/ /pubmed/35891856 http://dx.doi.org/10.7759/cureus.26158 Text en Copyright © 2022, Jordan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Jordan, Aryanna Makarova, Alena Adashek, Jacob J Guillain-Barré-Like Syndrome From Esophageal Squamous Cell Carcinoma |
title | Guillain-Barré-Like Syndrome From Esophageal Squamous Cell Carcinoma |
title_full | Guillain-Barré-Like Syndrome From Esophageal Squamous Cell Carcinoma |
title_fullStr | Guillain-Barré-Like Syndrome From Esophageal Squamous Cell Carcinoma |
title_full_unstemmed | Guillain-Barré-Like Syndrome From Esophageal Squamous Cell Carcinoma |
title_short | Guillain-Barré-Like Syndrome From Esophageal Squamous Cell Carcinoma |
title_sort | guillain-barré-like syndrome from esophageal squamous cell carcinoma |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306455/ https://www.ncbi.nlm.nih.gov/pubmed/35891856 http://dx.doi.org/10.7759/cureus.26158 |
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